Dengue fever in Czech travellers: A 10-year retrospective study in a tertiary care centre.

Autor: Trojánek M; 1st Department of Infectious Diseases, 2nd Medical Faculty, Charles University in Prague, Budínova 2, 180 81 Prague, Czech Republic; Department of Infectious, Parasitic and Tropical Diseases, Hospital Na Bulovce, Budínova 2, 180 81 Prague, Czech Republic. Electronic address: milan.trojanek@bulovka.cz., Maixner J; Department of Virology, Institute of Public Health in Ústí nad Labem, Budínova 2, 180 81 Prague, Czech Republic., Sojková N; Department of Virology, Institute of Public Health in Ústí nad Labem, Budínova 2, 180 81 Prague, Czech Republic., Kynčl J; Department of Epidemiology of Infectious Diseases, National Institute of Public Health, Šrobárova 48, 100 42 Prague, Czech Republic; Department of Epidemiology, 3rd Medical Faculty, Charles University in Prague, Ruská 87, 100 00 Prague, Czech Republic., Roháčová H; 1st Department of Infectious Diseases, 2nd Medical Faculty, Charles University in Prague, Budínova 2, 180 81 Prague, Czech Republic; Department of Infectious, Parasitic and Tropical Diseases, Hospital Na Bulovce, Budínova 2, 180 81 Prague, Czech Republic., Marešová V; 1st Department of Infectious Diseases, 2nd Medical Faculty, Charles University in Prague, Budínova 2, 180 81 Prague, Czech Republic; Department of Infectious, Parasitic and Tropical Diseases, Hospital Na Bulovce, Budínova 2, 180 81 Prague, Czech Republic., Stejskal F; 1st Department of Infectious Diseases, 2nd Medical Faculty, Charles University in Prague, Budínova 2, 180 81 Prague, Czech Republic; Department of Infectious, Parasitic and Tropical Diseases, Hospital Na Bulovce, Budínova 2, 180 81 Prague, Czech Republic; Institute of Immunology and Microbiology, 1st Medical Faculty, Charles University in Prague, Studničkova 7, 128 00 Prague, Czech Republic; Department of Infectious Diseases, Regional Hospital Liberec, Husova 10, 460 63 Liberec, Czech Republic.
Jazyk: angličtina
Zdroj: Travel medicine and infectious disease [Travel Med Infect Dis] 2016 Jan-Feb; Vol. 14 (1), pp. 32-38. Date of Electronic Publication: 2015 Jun 25.
DOI: 10.1016/j.tmaid.2015.06.005
Abstrakt: Background: Dengue fever is a frequent cause of morbidity in travellers. The objective was to describe the epidemiological and clinical characteristics of dengue fever in Czech travellers.
Method: This descriptive study includes patients with acute dengue fever diagnosed at Hospital Na Bulovce during 2004-2013. Data were collected and analysed retrospectively.
Results: A total of 132 patients (83 males and 49 females) of median age 33 years (IQR 29-40) were included. Diagnosis was established by NS1 antigen detection in 87/107 cases (81.3%) and/or RT-PCR in 50/72 (69.4%) and by serology in 25 cases (18.9%). Dengue was acquired in South-East Asia in 69 cases (52.3%), followed by South Asia (48 cases; 36.3%), Latin America (14; 10.6%) and Sub-Saharan Africa (1; 0.8%). The most frequent symptoms included fever, rash and headache. Initial leukocyte and lymphocyte counts were lower in patients who presented in the early phase (0-4 days), however, platelet count was lower and AST, ALT and LDH activity higher in patients with a longer symptoms duration (≥5 days). The clinical course was mostly uncomplicated.
Conclusions: Dengue fever is becoming a frequent cause of fever in Czech travellers. Clinicians should be familiar with the typical clinical findings and novel diagnostic methods.
(Copyright © 2015 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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