Risk factors and potential preventive measures for nephropatia epidemica in Sweden 2011-2012: a case-control study.

Autor:	Gherasim A; European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.; European Program for Intervention Epidemiology Training (EPIET), Stockholm, Sweden.; Swedish Institute for Communicable Disease Control (SMI), Solna, Sweden; amgherasim@externos.isciii.es., Hjertqvist M; Swedish Institute for Communicable Disease Control (SMI), Solna, Sweden., Lundkvist Å; Swedish Institute for Communicable Disease Control (SMI), Solna, Sweden.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.; Department of Microbiology, Karolinska Institute, Stockholm, Sweden., Kühlmann-Berenzon S; Swedish Institute for Communicable Disease Control (SMI), Solna, Sweden., Carlson JV; Swedish Institute for Communicable Disease Control (SMI), Solna, Sweden., Stenmark S; Department of Clinical Microbiology, Umeå University, Umeå, Sweden., Widerström M; Department of Clinical Microbiology, Umeå University, Umeå, Sweden.; Department of Communicable Disease Control and Prevention, Jämtland County Council, Östersund, Sweden., Österlund A; Department of Communicable Disease Control and Prevention, Norbotten County Council, Lulea, Sweden., Boman H; Department of Communicable Diseases Control and Prevention, Vasternorrland County Council, Matfors, Sweden., Ahlm C; Division of Infectious Diseases, Department of Clinical Microbiology, Umeå University Hospital, Umeå, Sweden., Wallensten A; Swedish Institute for Communicable Disease Control (SMI), Solna, Sweden.; Department of Medical Sciences, Infectious Diseases, Uppsala University, Uppsala, Sweden.
Jazyk:	angličtina
Zdroj:	Infection ecology & epidemiology [Infect Ecol Epidemiol] 2015 Jun 30; Vol. 5, pp. 27698. Date of Electronic Publication: 2015 Jun 30 (Print Publication: 2015).
DOI:	10.3402/iee.v5.27698
Abstrakt:	Introduction: Nephropatia epidemica (NE), a relatively mild form of hemorrhagic fever with renal syndrome caused by the Puumala virus (PUUV), is endemic in northern Sweden. We aim to study the risk factors associated with NE in this region. Methods: We conducted a matched case-control study between June 2011 and July 2012. We compared confirmed NE cases with randomly selected controls, matched by age, sex, and place of infection or residence. We analyzed the association between NE and several occupational, environmental, and behavioral exposures using conditional logistic regression. Results: We included in the final analysis 114 cases and 300 controls, forming 246 case-control pairs. Living in a house with an open space beneath, making house repairs, living less than 50 m from the forest, seeing rodents, and smoking were significantly associated with NE. Conclusion: Our results could orient public health policies targeting these risk factors and subsequently reduce the NE burden in the region.
Databáze:	MEDLINE
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