[Abnormal vaginal secretion: sensitivity, specificity and concordance between clinical and cytological diagnosis].

Autor:	de Camargo KC; Secretaria Municipal de Saúde de Goiânia, Goiânia, GO, Brasil., Alves RR; Departamento de Obstetrícia e Ginecologia, Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, GO, Brasil., Baylão LA; Secretaria Municipal de Saúde de Goiânia, Goiânia, GO, Brasil., Ribeiro AA; Departamento de Biomedicina, Pontifícia Universidade Católica de Goiás, Goiânia, GO, Brasil., Araujo NL; Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO, Brasil., Tavares SB; Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO, Brasil., dos Santos SH; Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO, Brasil.
Jazyk:	portugalština
Zdroj:	Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia [Rev Bras Ginecol Obstet] 2015 May; Vol. 37 (5), pp. 222-8.
DOI:	10.1590/SO100-720320150005183
Abstrakt:	Purpose: To estimate the prevalence of bacterial vaginosis (BV), candidiasis and trichomoniasis and compare the findings of physical examination of the vaginal secretion with the microbiological diagnosis obtained by cytology study of a vaginal smear using the Papanicolaou method. Methods: A cross-sectional study of 302 women aged 20 to 87 years, interviewed and submitted to a gynecology test for the evaluation of vaginal secretion and collection of a cytology smear, from June 2012 to May 2013. Sensitivity analyses were carried out and specificity, positive predictive value (PPV) and negative predictive value (NPV) with their respective 95%CI were determined to assess the accuracy of the characteristics of vaginal secretion in relation to the microbiological diagnosis of the cytology smear . The kappa index (k) was used to assess the degree of agreement between the clinical features of vaginal secretion and the microbiological findings obtained by cytology. RESULTS The prevalence of BV, candidiasis and trichomoniasis was 25.5, 9.3 and 2.0%, respectively. The sensitivity, specificity, PPV and NPV of the clinical characteristics of vaginal secretion for the cytological diagnosis of BV were 74, 78.6, 54.3 and 89.9%, respectively. The sensitivity, specificity, PPV and the NPV of the clinical characteristics of vaginal secretion for the cytological diagnosis of candidiasis were 46.4, 86.2, 25.5 and 94%, respectively. The correlation between the clinical evaluation of vaginal secretion and the microbiological diagnosis of BV, candidiasis and trichomoniasis, assessed by the kappa index, was 0.47, 0.23 and 0.28, respectively. CONCLUSION The most common cause of abnormal vaginal secretion was BV. The clinical evaluation of vaginal secretion presented amoderate to weak agreement with the microbiological diagnosis, indicating the need for complementary investigation of the clinical findings of abnormal vaginal secretion.
Databáze:	MEDLINE
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