Pancreatic mucinous cystic neoplasm in a transgender patient.

Autor: Foster D; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA., Shaikh MF; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA., Gleeson E; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA., Babcock BD; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA., Lin J; Department of Pathology, Drexel University College of Medicine, 254 N. 15th St, MS 435, Philadelphia, PA, 19102, USA., Ownbey RT; Department of Pathology, Drexel University College of Medicine, 254 N. 15th St, MS 435, Philadelphia, PA, 19102, USA., Hysell ME; Department of Diagnostic Radiology, Hahnemann University Hospital, 230 N. 15th St, MS 206, Philadelphia, PA, 19102, USA., Ringold D; Department of Medicine, Drexel University College of Medicine, 254 N. 15th St, MS 427, Philadelphia, PA, 19102, USA., Bowne WB; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA. wilbur.bowne@drexelmed.edu.
Jazyk: angličtina
Zdroj: World journal of surgical oncology [World J Surg Oncol] 2015 Jun 24; Vol. 13, pp. 205. Date of Electronic Publication: 2015 Jun 24.
DOI: 10.1186/s12957-015-0620-8
Abstrakt: Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females.
Case Presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy.
Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.
Databáze: MEDLINE