| Autor: |
Reziapkin VI, Gurinovich VA, Chiger VB, Moiseenok AG |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy pitaniia [Vopr Pitan] 1989 Sep-Oct (5), pp. 50-3. |
| Abstrakt: |
Experiments were conducted on white rats given synthetic rations devoid of pantothenic acid during 10 weeks. Intensification of 14C-pantothenate deposition was recorded 30 min and 4 h after its intraperitoneal administration. The mitochondrial fraction of the liver accumulated the isotope in time. High-performance liquid chromatography used for separation of the vitamin labeled metabolites has revealed phosphopantothenate (pantothenate), phosphopantothein, CoA and dephospho-CoA (pantetein) in the liver homogenate, while in the mitochondria extracts only CoA and dephospho-CoA (pantetein) were detected. It has been suggested that dephosphorylation of pantothenate metabolites and rapid transformation of phosphopantetein into CoA may take place during the separation of the fractions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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