Pediatric recurrent laryngeal nerve reinnervation: A case series and analysis of post-operative outcomes.

Autor: Farhood Z; The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Reusser NM; The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Bender RW; The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Thekdi AA; Texas Voice Center, Houston, TX 77030, USA., Albright JT; The Department of Otolaryngology-Head & Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA., Edmonds JL; The Department of Otolaryngology-Head & Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: jedmonds337@gmail.com.
Jazyk: angličtina
Zdroj: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2015 Aug; Vol. 79 (8), pp. 1320-3. Date of Electronic Publication: 2015 Jun 09.
DOI: 10.1016/j.ijporl.2015.06.001
Abstrakt: Objective: To provide detailed information about recurrent laryngeal nerve (RLN) reinnervation outcomes in children using objective measures.
Methods: The records of three pediatric patients with unilateral vocal cord paralysis that underwent RLN reinnervation were retrospectively reviewed. Fundamental frequency (F0), jitter, shimmer, noise-to-harmonic ratio (NHR), and voice phonation (sustained /s/, /z/, /a/) were measured preoperatively and post-operatively at 13, 9, and 33 months (each time period corresponding to one of the three patients).
Results: Mean preoperative and post-operative variables were as follows: shimmer, 9.65±1.02% vs. 4.46±0.71% (p=0.01); NHR, 0.296±0.063 vs. 0.127±0.011 (p=0.04); jitter, 3.57±0.89% vs. 1.46±0.54% (p=0.08); F0, 274.6±35.4Hz vs. 282.2±70.6Hz (p=0.44); maximum phonation time, 7.46±1.40s vs. 9.79±1.84s (p=0.22); /s:z/ ratio, 1.28±0.22 vs.1.07±0.09 (p=0.26).
Conclusions: There was statistically significant improvement in shimmer and NHR. Jitter improvement approached statistical significance. All other variables failed to show significant improvement among this small sample size. RLN reinnervation for pediatric patients is an option for the treatment of vocal cord paralysis. Further studies with larger cohorts are needed to show the full benefits.
(Copyright © 2015. Published by Elsevier Ireland Ltd.)
Databáze: MEDLINE
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