Enantioselective Hydroformylation of 1-Alkenes with Commercial Ph-BPE Ligand.
| Autor: | Yu Z; Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States., Eno MS; Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States., Annis AH; Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States., Morken JP; Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States. |
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| Jazyk: | angličtina |
| Zdroj: | Organic letters [Org Lett] 2015 Jul 02; Vol. 17 (13), pp. 3264-7. Date of Electronic Publication: 2015 Jun 19. |
| DOI: | 10.1021/acs.orglett.5b01421 |
| Abstrakt: | A rhodium complex, in conjunction with commercially available Ph-BPE ligand, catalyzes the branch-selective asymmetric hydroformylation of 1-alkenes and rapidly generates α-chiral aldehydes. A wide range of terminal olefins including 1-dodecene were examined, and all delivered high enantioselectivity (up to 98:2 er) as well as good branch:linear ratios (up to 15:1). |
| Databáze: | MEDLINE |
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