[Use of sugammadex in burn patients: descriptive study].

Autor: Rodríguez Sánchez M E; Anestesiologia e Reanimação, Hospitais Universitários Virgen del Rocío, Sevilha, Espanha. Electronic address: edurodriguez87@yahoo.es., Martínez Torres C; Anestesiologia e Reanimação, Hospitais Universitários Virgen del Rocío, Sevilha, Espanha., Herrera Calo P; Anestesiologia e Reanimação, Hospitais Universitários Virgen del Rocío, Sevilha, Espanha., Jiménez I; Anestesiologia e Reanimação, Hospitais Universitários Virgen del Rocío, Sevilha, Espanha.
Jazyk: portugalština
Zdroj: Revista brasileira de anestesiologia [Rev Bras Anestesiol] 2015 Jul-Aug; Vol. 65 (4), pp. 240-3. Date of Electronic Publication: 2015 Jun 10.
DOI: 10.1016/j.bjan.2014.10.003
Abstrakt: Objectives: The burn patient is a challenge for the anesthesiologist, undergoing several surgeries during admission, and requiring general anesthesia and muscle relaxation most of the times. They have respiratory system impairment and a response to muscle relaxants that differs from the healthy patient, thus proper monitoring and reversal is crucial. We analyzed sugammadex effectiveness and safety in this population.
Material and Methods: Prospectively descriptive study including four patients, all of them considered major burn patients, who underwent escharotomy with general anesthesia and neuromuscular relaxation. The main variable was the time for recovery of a TOF higher than 0.9 after the administration of sugammadex before extubation.
Results: Mean time of recovery from a TOF ratio higher than 0.9 following the administration of Sugammadex was of 4.95minutes 95% CI (3.25-6.64, p=.53);
Conclusions: The reversion of neuromuscular relaxation with sugammadex appears to be effective and safe in the burn patient. More analytical, comparative studies, of larger populations would be necessary to confirm this data.
(Copyright © 2015 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.)
Databáze: MEDLINE