Bovine Collagen Xenograft Repair of Extensive Surgical Scalp Wounds With Exposed Calvarium in the Elderly: Increased Rates of Wound Healing.
| Autor: | Rogge MN; Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York; †Division of Mohs Surgery and Cutaneous Oncology, Department of Dermatology, Stony Brook University Hospital, Stony Brook, New York; ‡Division of Dermatology, Department of Internal Medicine, Washington University, St. Louis, Missouri; §Mohs Surgery and Cutaneous Oncology Service, Department of Dermatology, Saint Louis University, St. Louis, Missouri; Departments of ‖Ophthalmology, ¶Internal Medicine, and #Otolaryngology-Head and Neck Surgery, Saint Louis University, St. Louis, Missouri; **Cancer Center, Saint Louis University, St. Louis, Missouri., Slutsky JB, Council ML, Fosko SW |
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| Jazyk: | angličtina |
| Zdroj: | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2015 Jul; Vol. 41 (7), pp. 794-802. |
| DOI: | 10.1097/DSS.0000000000000374 |
| Abstrakt: | Background: Postsurgical scalp wounds that extend to the calvarium present a challenge for repair, especially in the elderly patient with multiple comorbidites. When second-intention healing is selected for closure, patients often have prolonged healing times. Objective: To assess the clinical outcomes of animal-derived collagen xenograft placement on postsurgical scalp wounds extending to the calvarium. Methods: Eleven patients (ages, 61 through 95 years) with calvarium-exposed wounds treated solely with bovine-derived collagen xenografts were reviewed with follow-up extending 12 to 30 weeks after initial surgery. Results: Increased rates of healing were found in the xenograft-treated wounds as compared with previous studies of calvarium-exposed wounds healed by second intention alone. Advantages of animal-derived collagen xenografts include immediate coverage of the wound, simple application, low cost, and avoidance of the morbidity associated with local flap, graft, and free flap repairs. Conclusion: In patients with postsurgical scalp defects with exposed calvarium, collagen xenograft placement may expedite second-intention healing and offer other advantages in the elderly population. |
| Databáze: | MEDLINE |
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