Platelet function parameters in management of hepatic hydatid disease: a case-controlled study.

Autor:	Dinc B; Department of Surgery, Ataturk State Hospital Antalya 07040, Turkey., Dusen S; Department of Biology, Pamukkale University, Faculty of Arts and Sciences Denizli 20070, Turkey., Ay N; Department of Surgery, Diyarbakir Training and Research Hospital Diyarbakir 21010, Turkey., Dinc SE; Department of Emergency, Isparta State Hospital Isparta 32100, Turkey., Mayir B; Department of Surgery, Antalya Training and Research Hospital Diyarbakir 07050, Turkey., Gunduz UR; Department of Surgery, Antalya Training and Research Hospital Diyarbakir 07050, Turkey., Musri OC; Department of Surgery, Ataturk State Hospital Antalya 07040, Turkey., Bas B; Department of Gastroenterology, Ataturk State Hospital Antalya 07040, Turkey., Dogan U; Department of Surgery, Antalya Training and Research Hospital Diyarbakir 07050, Turkey., Oskay A; Department of Emergency, Denizli State Hospital Denizli 20010, Turkey.
Jazyk:	angličtina
Zdroj:	International journal of clinical and experimental medicine [Int J Clin Exp Med] 2015 Mar 15; Vol. 8 (3), pp. 3869-75. Date of Electronic Publication: 2015 Mar 15 (Print Publication: 2015).
Abstrakt:	Aim: To evaluate platelet function in patients with a history of surgical treatment for hepatic hydatid disease (HD). Methods: This retrospective case-controlled study was performed in a state hospital in Turkey from January 2009 to November 2013. The patients were divided into two groups: those evaluated in the preoperative period (Group 1) and those evaluated in the postoperative period (Group 2). The patient groups were compared with a control group (Group 3). All three groups were evaluated using laboratory records from day 1 of the preoperative period and day 30 of the postoperative period. The haematocrit level (HTC), platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), and percentage of eosinophils (EOS) were compared among the groups. Results: Fifty-three patients who had undergone surgical treatment of hepatic HD and 55 healthy controls were included in the study. The mean follow-up time for all patients was 45 (14-70) months. The patients comprised 33 (62%) females and 20 (38%) males. The control group comprised 37 (67%) females and 18 (33%) males. The median age of the patients was 48 (19-78) years, while that of the control group was 42 (16-64) years. No significant differences in the HTC, PLT, or EOS were present among the groups. The MPV and PDW indicated that platelet function was significantly different between Group 1 and Groups 2 and 3. Additionally, nine patients had undergone previous surgical treatment for HD. In a separate long-term follow-up, these patients exhibited no statistically significant differences in MPV or PDW between the preoperative and postoperative periods. Conclusions: MPV and PDW can be used in the initial follow-up of patients with hepatic HD, but have limited use in long-term follow-up.
Databáze:	MEDLINE
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