Investigating nasal cytology as a potential tool for diagnosing occupational rhinitis in woodworkers.

Autor: Staffieri C; Department of Neurosciences, Otolaryngology Section, Treviso Regional Hospital Branch, University of Padova, Treviso, Italy., Lovato A; Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy., Aielli F; Department of Neurosciences, Otolaryngology Section, Treviso Regional Hospital Branch, University of Padova, Treviso, Italy., Bortoletto M; Department of Cardiologic, Thoracic and Vascular Sciences, Preventive Medicine and Risk Assessment Unit, University of Padova, Padova, Italy., Giacomelli L; Department of Medicine, University of Padova, Padova, Italy., Carrieri M; Department of Cardiologic, Thoracic and Vascular Sciences, Preventive Medicine and Risk Assessment Unit, University of Padova, Padova, Italy., Romeo S; Department of Pathology, Treviso Regional Hospital, Treviso, Italy., Boscolo-Rizzo P; Department of Neurosciences, Otolaryngology Section, Treviso Regional Hospital Branch, University of Padova, Treviso, Italy., Da Mosto MC; Department of Neurosciences, Otolaryngology Section, Treviso Regional Hospital Branch, University of Padova, Treviso, Italy., Bartolucci GB; Department of Cardiologic, Thoracic and Vascular Sciences, Preventive Medicine and Risk Assessment Unit, University of Padova, Padova, Italy., Marioni G; Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy., Scapellato ML; Department of Cardiologic, Thoracic and Vascular Sciences, Preventive Medicine and Risk Assessment Unit, University of Padova, Padova, Italy.
Jazyk: angličtina
Zdroj: International forum of allergy & rhinology [Int Forum Allergy Rhinol] 2015 Sep; Vol. 5 (9), pp. 814-9. Date of Electronic Publication: 2015 Jun 05.
DOI: 10.1002/alr.21562
Abstrakt: Background: Our primary endpoint was to use nasal cytology to compare woodworkers with unexposed subjects to see if wood dust exposure correlates with specific patterns of inflammatory or infectious rhinitis. A secondary endpoint was to identify any differences in the exposed group's nasal symptoms or nasal cytology by years of exposure or personal exposure levels.
Methods: Ninety-two woodworkers and 90 controls were assessed using a questionnaire and nasal cytology (on nasal mucosa obtained by scraping). Wood dust exposure was investigated using personal sampling methods.
Results: Woodworkers reported significantly more nasal symptoms than controls (p < 0.00001). The woodworkers' nasal smears revealed more neutrophils (p = 0.001) and significantly higher mean neutrophil scores (p = 0.001) than control smears. Lymphocytes were also found more often in the woodworkers' rhinocytograms (statistical trend, p = 0.06). Neutrophilic rhinitis was diagnosed more frequently in the exposed workers than in controls (chi-square = 5.97, p < 0.05). Woodworkers with lymphocytes in their nasal smears had been exposed to wood dust for longer periods of time (statistical trend; p = 0.06). No differences in nasal symptoms or cell counts emerged when woodworkers were stratified by levels of personal exposure.
Conclusion: Nasal cytology should be further investigated in woodworkers before considering it a screening method for identifying woodworkers with chronic inflammatory rhinitis.
(© 2015 ARS-AAOA, LLC.)
Databáze: MEDLINE
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