Catalytic Ketone Hydrodeoxygenation Mediated by Highly Electrophilic Phosphonium Cations.

Autor: Mehta M; Department of Chemistry, University of Toronto, 80 St. George St, Toronto Ontario M5S 3H6 (Canada)., Holthausen MH; Department of Chemistry, University of Toronto, 80 St. George St, Toronto Ontario M5S 3H6 (Canada)., Mallov I; Department of Chemistry, University of Toronto, 80 St. George St, Toronto Ontario M5S 3H6 (Canada)., Pérez M; Department of Chemistry, University of Toronto, 80 St. George St, Toronto Ontario M5S 3H6 (Canada)., Qu ZW; Mulliken Center for Theoretical Chemistry, Institut für Physikalische und Theoretische Chemie, Universität Bonn, Beringstrasse 4, 53115 Bonn (Germany)., Grimme S; Mulliken Center for Theoretical Chemistry, Institut für Physikalische und Theoretische Chemie, Universität Bonn, Beringstrasse 4, 53115 Bonn (Germany)., Stephan DW; Department of Chemistry, University of Toronto, 80 St. George St, Toronto Ontario M5S 3H6 (Canada). dstephan@chem.utoronto.ca.
Jazyk: angličtina
Zdroj: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2015 Jul 06; Vol. 54 (28), pp. 8250-4. Date of Electronic Publication: 2015 Jun 01.
DOI: 10.1002/anie.201502579
Abstrakt: Ketones are efficiently deoxygenated in the presence of silane using highly electrophilic phosphonium cation (EPC) salts as catalysts, thus affording the corresponding alkane and siloxane. The influence of distinct substitution patterns on the catalytic effectiveness of several EPCs was evaluated. The deoxygenation mechanism was probed by DFT methods.
(© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Databáze: MEDLINE
Externí odkaz: