Autor: |
Marzuka AG; Department of Dermatology, Yale School of Medicine, New Haven, Connecticut ; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut., Book SE; Department of Dermatology, Yale School of Medicine, New Haven, Connecticut. |
Jazyk: |
angličtina |
Zdroj: |
The Yale journal of biology and medicine [Yale J Biol Med] 2015 Jun 01; Vol. 88 (2), pp. 167-79. Date of Electronic Publication: 2015 Jun 01 (Print Publication: 2015). |
Abstrakt: |
Basal cell carcinoma (BCC) is the most common malignancy. Exposure to sunlight is the most important risk factor. Most, if not all, cases of BCC demonstrate overactive Hedgehog signaling. A variety of treatment modalities exist and are selected based on recurrence risk, importance of tissue preservation, patient preference, and extent of disease. The pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management of BCC will be discussed in this review. |
Databáze: |
MEDLINE |
Externí odkaz: |
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