Autor: |
Martusevich AK, Soloveva AG, Ashikhmin SP, Peretyagin SP |
Jazyk: |
ruština |
Zdroj: |
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2015 Feb; Vol. 101 (2), pp. 180-8. |
Abstrakt: |
The aim of this work was the investigation of nitric oxide (NO) inhalations action on some parameters of energy and oxidative metabolism of healthy rats blood. Wistar rats were randomly divided into two groups: control group (without any manipulations; n = 10) and main group (n = 10) with inhalations by NO-containing gas flow (20 ppm). Activity of pro- and antioxidant systems, superoxide dismutase, lactate dehydrogenase and lactate level were estimated in rats blood samples. We observed stimulation of adaptive reserves of rats organism after course of NO (20 ppm) inhalations. First component of these changes was a modulation of pro- and antioxidant systems, including intensification of lipid peroxidation with prevalent activation of superoxide dismutase. Second component was a positive modification of lactate dehydrogenase functioning. |
Databáze: |
MEDLINE |
Externí odkaz: |
|