Rituximab in two cases of Goodpasture's syndrome.
| Autor: | Schless B; Division of Nephrology, Medical Department , University Hospital, Ulm., Yildirim S; Division of Nephrology, Medical Department , University Hospital, Ulm., Beha D; Division of Nephrology, Medical Department , University Hospital, Ulm., Keller F; Division of Nephrology, Medical Department , University Hospital, Ulm., Czock D; Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology , University Hospital Heidelberg , Heidelberg , Germany. |
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| Jazyk: | angličtina |
| Zdroj: | NDT plus [NDT Plus] 2009 Jun; Vol. 2 (3), pp. 225-7. Date of Electronic Publication: 2009 Feb 18. |
| DOI: | 10.1093/ndtplus/sfp020 |
| Abstrakt: | We describe the effects of rituximab in two patients with refractory Goodpasture's syndrome. After one single 1000 mg dose administration, rituximab did not appear to improve renal function in either of our cases. Polyoma virus-negative leukoencephalopathy, a probable toxic side effect of rituximab, was seen in our first patient. |
| Databáze: | MEDLINE |
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