| Autor: |
Nagashima S; Dept. of Pharmacy, National Hospital Organization Kure Medical Center and Chugoku Cancer Center., Kiba T, Ogawa Y, Mura T, Kajiume S, Okada Y, Morii N, Takahashi H, Ichiba Y, Yamashiro H |
| Jazyk: |
japonština |
| Zdroj: |
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2015 May; Vol. 42 (5), pp. 617-9. |
| Abstrakt: |
Here, we report about a 60-year-old woman with metastatic breast cancer who was successfully treated for paclitaxelinduced peripheral neuropathy with duloxetine. She was administered trastuzumab plus paclitaxel(PTX)combination therapy that was ultimately discontinued because of grade 3 peripheral neuropathy detected on day 15, according to the CTCAE (v4.0). She was administered duloxetine on day 90 after the end of the previous therapy because of the peripheral neuropathy. Thereafter, the peripheral neuropathy decreased to grade 1, which enabled PTX administration on her request. Further trials are required to confirm the efficacy of duloxetine. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
