Molecular cloning of the Rauscher murine leukemia virus. Disease spectrum and integration pattern.

Autor: van der Feltz MJ; Department of Pathology, Faculty of Medicine, Erasmus University Rotterdam, The Netherlands., Kranendonk-Odijk ME, Rhijnsburger EH, Stark J, Stoker K, de Both NJ
Jazyk: angličtina
Zdroj: Archives of virology [Arch Virol] 1989; Vol. 108 (1-2), pp. 115-20.
DOI: 10.1007/BF01313748
Abstrakt: After transfection of NIH 3T3 cells with DNA from molecularly cloned Rauscher MuLV, virus was isolated which showed a disease spectrum comparable to that of R-MuLV cloned biologically by endpoint dilution. In both cases sites of proviral integration vary from 2-5 per leukemic tissue and occur apparently at random.
Databáze: MEDLINE