Voice Formants in Individuals With Congenital, Isolated, Lifetime Growth Hormone Deficiency.

Autor: Valença EH; Department of Speech and Hearing Therapy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil. Electronic address: eugeniaherminia@bol.com.br., Salvatori R; Division of Endocrinology, Department of Medicine, The Johns Hopkins University, School of Medicine, Baltimore, Maryland., Souza AH; Division of Endocrinology, Department of Medicine, Federal University of Sergipe, Aracaju, Sergipe, Brazil., Oliveira-Neto LA; Department of Dentistry, Federal University of Sergipe, Aracaju, Sergipe, Brazil., Oliveira AH; Department of Dentistry, Federal University of Sergipe, Aracaju, Sergipe, Brazil., Gonçalves MI; Department of Speech and Hearing Therapy, Federal University of São Paulo, São Paulo, Brazil., Oliveira CR; Division of Endocrinology, Department of Medicine, Federal University of Sergipe, Aracaju, Sergipe, Brazil., D'Ávila JS; Division of Otorhinolaryngology, Department of Medicine, Federal University of Sergipe, Aracaju, Sergipe, Brazil., Melo VA; Department of Medicine, Federal University of Sergipe, Aracaju, Sergipe, Brazil., de Carvalho S; Department of Speech and Hearing Therapy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., de Andrade BM; Department of Speech and Hearing Therapy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., Nascimento LS; Department of Speech and Hearing Therapy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., Rocha SB; Department of Speech and Hearing Therapy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., Ribeiro TR; Department of Speech and Hearing Therapy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., Prado-Barreto VM; Division of Otorhinolaryngology, Department of Medicine, Federal University of Sergipe, Aracaju, Sergipe, Brazil., Melo EV; Department of Medicine, Federal University of Sergipe, Aracaju, Sergipe, Brazil., Aguiar-Oliveira MH; Division of Endocrinology, Department of Medicine, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Jazyk: angličtina
Zdroj: Journal of voice : official journal of the Voice Foundation [J Voice] 2016 May; Vol. 30 (3), pp. 281-6. Date of Electronic Publication: 2015 May 04.
DOI: 10.1016/j.jvoice.2015.03.015
Abstrakt: Objective: To analyze the voice formants (F1, F2, F3, and F4 in Hz) of seven oral vowels, in Brazilian Portuguese, [a, ε, e, i, ɔ, o, and u] in adult individuals with congenital lifetime untreated isolated growth hormone deficiency (IGHD).
Study Design: This is a cross-sectional study.
Methods: Acoustic analysis of isolated vowels was performed in 33 individuals with IGHD, age 44.5 (17.6) years (16 women), and 29 controls, age 51.1 (17.6) years (15 women).
Results: Compared with controls, IGHD men showed higher values of F3 [i, e, and ε], P = 0.006, P = 0.022, and P = 0.006, respectively and F4 [i], P = 0.001 and lower values of F2 [u], P = 0.034; IGHD women presented higher values of F1 [i and e] P = 0.029 and P = 0.036; F2 [ɔ] P = 0.006; F4 [ɔ] P = 0.031 and lower values of F2 [i] P = 0.004. IGHD abolished most of the gender differences in formant frequencies present in controls.
Conclusions: Congenital, severe IGHD results in higher values of most formant frequencies, suggesting smaller oral and pharyngeal cavities. In addition, it causes a reduction in the effect of gender on the structure of the formants, maintaining a prepubertal acoustic prediction.
(Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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