| Autor: |
Braswell MA, McCowan NK, Schulmeier JS, Brodell RT; Division of Dermatology, University of Mississippi Medical Center, 2500 N State St, Jackson, MS 39216, USA. rbrodell@umc.edu. |
| Jazyk: |
angličtina |
| Zdroj: |
Cutis [Cutis] 2015 Apr; Vol. 95 (4), pp. 237-40. |
| Abstrakt: |
Dermatologists often perform 2 biopsies in patients with widespread tense blisters: one for light microscopy and another for direct immunofluorescence (DIF). Biopsy techniques recommended for blistering diseases with tense blisters are discussed, and illustrations demonstrate an alternative approach utilizing a single punch biopsy. A single punch biopsy is more cost effective and provides the same diagnostic information as the standard 2-biopsy approach for subepidermal blisters plus additional salt-split skin-like diagnostic information. A limitation for bisecting the single punch biopsy specimen is a potential complete separation of the epidermis from the dermis. The single punch biopsy technique is a simple cost-effective method for obtaining necessary diagnostic information when sampling tense blisters in patients with blistering diseases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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