High dietborne Cu and Cd induced genotoxicity of Nile tilapia (Oreochromis niloticus).

Autor: El-Serafy SS; Department of Zoology, Faculty of Science, University of Benha, Benha, Egypt., Zowail ME; Department of Zoology, Faculty of Science, University of Benha, Benha, Egypt., Abdel-Hameid NA; Department of Zoology, Faculty of Science, University of Benha, Benha, Egypt. Electronic address: nassr65@gmail.com., Awwad MH; Department of Zoology, Faculty of Science, University of Benha, Benha, Egypt., Nafie EH; Department of Zoology, Faculty of Science, University of Benha, Benha, Egypt.
Jazyk: angličtina
Zdroj: Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2015 May; Vol. 39 (3), pp. 1139-47. Date of Electronic Publication: 2015 Apr 13.
DOI: 10.1016/j.etap.2015.04.001
Abstrakt: In this study, the effects of fish diet contaminated with Cu, Cd and Cu+Cd on Nile tilapia, was demonstrated by evaluating its bioaccumulation in the muscle and by testing the cytogenetic profile. Fish exposed to diet contaminated with Cu, Cd or their mixture had a significant increase in the number of chromosomal abnormalities and an inhibition of the mitotic index. Our study revealed high muscle Cu or Cd content in fish fed with diet contaminated with high dietborne Cu, Cd, Cu and Cd. It also revealed that the chromosomal abnormalities were higher for fish fed diet Cd contaminated and Cu+Cd contaminated diets than those fed diet Cu contaminated diet. Thus, maybe fish diets contaminated with Cu, Cd, Cu+Cd induced genotoxicity and mutation. Also, maybe high concentrations of Cu and Cd in fish tissue resulted from feeding on Cu and Cd contaminated diets, are dangerous for human consumption.
(Copyright © 2015 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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