The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology.
| Autor: | Gelen SA; Kocaeli University Faculty of Medicine Hospital, Department of Pediatrics, Division of Pediatric Hematology, Kocaeli, Turkey Phone: +90 532 596 25 54 E-mail: semaylan@hotmail.com., Sarper N, Demirsoy U, Zengin E, Çakmak E |
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| Jazyk: | angličtina |
| Zdroj: | Turkish journal of haematology : official journal of Turkish Society of Haematology [Turk J Haematol] 2015 Dec; Vol. 32 (4), pp. 351-4. Date of Electronic Publication: 2015 Apr 27. |
| DOI: | 10.4274/tjh.2014.0149 |
| Abstrakt: | Objective: The aim of this study is to investigate the efficacy and safety of sedoanalgesia performed outside the operating room by pediatricians trained in advanced airway management and life support. Materials and Methods: Midazolam and ketamine were administered consecutively by intravenous route under cardiorespiratory monitoring for painful procedures of pediatric hematology. Results: A total of 115 patients had 237 sedoanalgesia sessions. Sedation time was 24.02±23.37 s and sedation success was 92.5% (Ramsay scores of ≥5). Patient satisfaction was high. The recovery time was 28.81±14.4 min. Although statistically significant (p<0.01) increases in systolic and diastolic blood pressure, heart rate, and respiratory rate were observed without clinical importance, they improved without any intervention. No severe adverse events were observed. Conclusion: Sedoanalgesia with intravenous midazolam and ketamine for pediatric hematology and oncology patients' painful minor invasive procedures performed in an optimally equipped setting outside the operating room by pediatricians trained and certificated in advanced airway management and life support is effective and safe. |
| Databáze: | MEDLINE |
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