Frequent house invasion of Trypanosoma cruzi-infected triatomines in a suburban area of Brazil.

Autor: Ribeiro G Jr; Laboratório de Patologia e Biologia Molecular, Centro de Pesquisas Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brazil; Faculdade Ruy Barbosa DeVry, Salvador, Bahia, Brazil., Gurgel-Gonçalves R; Laboratório de Parasitologia Médica e Biologia de Vetores, Universidade de Brasília, Brasília, Brazil., Reis RB; Laboratório de Patologia e Biologia Molecular, Centro de Pesquisas Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brazil; Programa de Pós Graduação em Desenvolvimento Regional e Urbano (PPDRU), Unifacs, Universidade Salvador, Salvador, Bahia, Brazil., Santos CG; Laboratório de Patologia e Biologia Molecular, Centro de Pesquisas Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brazil; Laboratório de Entomologia, Laboratório Central de Saúde Pública do Estado da Bahia, Secretaria da Saúde, Salvador, Bahia, Brazil., Amorim A; Laboratório de Patologia e Biologia Molecular, Centro de Pesquisas Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brazil., Andrade SG; Laboratório de Doença de Chagas Experimental, Autoimunidade e Imunologia Celular, FIOCRUZ-BA, Salvador, Bahia, Brazil., Reis MG; Laboratório de Patologia e Biologia Molecular, Centro de Pesquisas Gonçalo Moniz, FIOCRUZ-BA, Salvador, Bahia, Brazil.
Jazyk: angličtina
Zdroj: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2015 Apr 24; Vol. 9 (4), pp. e0003678. Date of Electronic Publication: 2015 Apr 24 (Print Publication: 2015).
DOI: 10.1371/journal.pntd.0003678
Abstrakt: Background: The demographic transition of populations from rural areas to large urban centers often results in a disordered occupation of forest remnants and increased economic pressure to develop high-income buildings in these areas. Ecological and socioeconomic factors associated with these urban transitions create conditions for the potential transmission of infectious diseases, which was demonstrated for Chagas disease.
Methodology/principal Findings: We analyzed 930 triatomines, mainly Triatoma tibiamaculata, collected in artificial and sylvatic environments (forests near houses) of a suburban area of the city of Salvador, Bahia State, Brazil between 2007 and 2011. Most triatomines were captured at peridomiciles. Adult bugs predominated in all studied environments, and nymphs were scarce inside houses. Molecular analyses of a randomly selected sub-sample (n=212) of triatomines showed Trypanosoma cruzi infection rates of 65%, 50% and 56% in intradomestic, peridomestic and sylvatic environments, respectively. We detected the T. cruzi lineages I and II and mixed infections. We also showed that T. tibiamaculata fed on blood from birds (50%), marsupials (38%), ruminants (7%) and rodents (5%). The probability of T. cruzi infection was higher in triatomines that fed on marsupial blood (odds ratio (OR) = 1.95, 95% confidence interval (CI) = 1.22-3.11). Moreover, we observed a protective effect against infection in bugs that fed on bird blood (OR = 0.43, 95% CI = 0.30-0.73).
Conclusions/significance: The frequent invasion of houses by infected triatomines indicates a potential risk of T. cruzi transmission to inhabitants in this area. Our results reinforce that continuous epidemiological surveillance should be performed in areas where domestic transmission is controlled but enzootic transmission persists.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje