Randomized trial of the effectiveness of a non-pharmacological multidisciplinary face-to-face treatment program on daily function compared to a telephone-based treatment program in patients with generalized osteoarthritis.

Autor: Cuperus N; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands. Electronic address: n.cuperus@maartenskliniek.nl., Hoogeboom TJ; Department of Epidemiology, CAPHRI School for Public Health and Primary Care, CCTR Centre for Care Technology Research, Maastricht University, The Netherlands. Electronic address: thomashoogeboom@gmail.com., Kersten CC; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands. Electronic address: c.kersten@maartenskliniek.nl., den Broeder AA; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands. Electronic address: a.denbroeder@maartenskliniek.nl., Vlieland TP; Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands. Electronic address: t.p.m.vliet_vlieland@lumc.nl., van den Ende CH; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands. Electronic address: e.vandenende@maartenskliniek.nl.
Jazyk: angličtina
Zdroj: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2015 Aug; Vol. 23 (8), pp. 1267-75. Date of Electronic Publication: 2015 Apr 14.
DOI: 10.1016/j.joca.2015.04.007
Abstrakt: Objective: To compare the effectiveness of a non-pharmacological multidisciplinary face-to-face self-management treatment program with a telephone-based program on daily function in patients with generalized osteoarthritis (GOA).
Design: A pragmatic single-blind randomized clinical superiority trial involving 147 patients clinically diagnosed with GOA, randomly allocated to either a 6 week non-pharmacological multidisciplinary face-to-face treatment program comprising seven group sessions or a 6 week telephone-based treatment program comprising two group sessions combined with four telephone contacts. Both programs aimed to improve daily function and to enhance self-management to control the disease. The programs critically differed in mode of delivery and intensity. Daily function (primary outcome) and secondary outcomes were assessed at baseline, 6, 26 and 52 weeks. Data were analyzed using linear or logistic multilevel regression models corrected for baseline, sex and group-wise treatment.
Results: No differences in effectiveness between both treatment programs were observed on the primary outcome (group difference (95% CI): -0.03 (-0.14, 0.07)) or on secondary outcome measures, except for a larger improvement in pain in the face-to-face treatment group (group difference (95% CI): 1.61 (0.01, 3.21)). Within groups, significant improvements were observed on several domains, especially in the face-to-face group. However, these benefits are relatively small and unlikely to be of clinical importance.
Conclusions: We found no differences in treatment effect between patients with GOA who followed a non-pharmacological multidisciplinary face-to-face self-management program and those who received a telephone-delivered program. Besides, our findings demonstrated limited benefits of a self-management program for individuals with GOA. Dutch Trial Register trial number: NTR2137.
(Copyright © 2015 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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