| Autor: |
Wilcox JR; Healogics, Inc, Jacksonville, FL; email: jrwilcox1120@yahoo.com., Covington DS; Healogics, Inc, Jacksonville, FL., Paez N; Healogics, Inc, Jacksonville, FL. |
| Jazyk: |
angličtina |
| Zdroj: |
Wounds : a compendium of clinical research and practice [Wounds] 2012 Dec; Vol. 24 (12), pp. 339-49. |
| Abstrakt: |
Doxycycline is a semisynthetic, chemically modified tetracycline compound that is rapidly absorbed and exerts biological effects independent of its antimicrobial activity. One such effect includes the inhibition of matrix metalloproteinases. Doxycycline has a long history as a collagenase inhibitor. This article will describe its mode of action and review its effectiveness in significantly reducing inflammation and elevated levels of proinflammatory cytokines within chronic wounds. . |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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