Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room.

Autor: Morotti A; Department of Internal Medicine, San Luigi Hospital, University of Turin , Italy., Frascisco MF; Department of Internal Medicine, San Luigi Hospital, University of Turin , Italy.
Jazyk: angličtina
Zdroj: Hematology reports [Hematol Rep] 2015 Mar 09; Vol. 7 (1), pp. 5656. Date of Electronic Publication: 2015 Mar 09 (Print Publication: 2015).
DOI: 10.4081/hr.2015.5656
Abstrakt: Life-threatening bleeding in anticoagulation with Warfarin is an emergency challenging issue. Several approaches are available to treat bleeding in either over-anticoagulation or proper-anticoagulation, including vitamin K, fresh frozen plasma and prothrombin complex concentrates (PCC) administration. In coexisting trauma-induced bleeding and anticoagulation, reversal of anticoagulation must be a rapid and highly effective procedure. Furthermore the appropriate treatment must be directly available in each shock rooms to guarantee the rapid management of the emergency. PCC require a simple storage, rapid accessibility, fast administration procedures and high effectiveness. Here we report the utility of PCC in management of a craniofacial trauma in proper-anticoagulation.
Databáze: MEDLINE