| Autor: |
Tagliolatto S; Campinas, Campinas, SP, Brazil., Santos Neto Ode O; Universidade Estadual de Campinas, Campinas, SP, Brazil., Alchorne MM; Universidade Federal de São Paulo, São Paulo, SP, Brazil., Enokihara MY; Universidade Federal de São Paulo, São Paulo, SP, Brazil. |
| Jazyk: |
angličtina |
| Zdroj: |
Anais brasileiros de dermatologia [An Bras Dermatol] 2015 Mar-Apr; Vol. 90 (2), pp. 211-5. |
| DOI: |
10.1590/abd1806-4841.20153192 |
| Abstrakt: |
The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. The average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. The statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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