Prevalence and type of associated syndromes in patients with cleft lip and cleft palate who received the treatment in Tawanchai Center until 4-5 years of age.

Autor:	Wichajarn K, Panamonta O, Pradubwong S, Panamonta M, Weraarchakul W, Chowchuen B
Jazyk:	angličtina
Zdroj:	Journal of the Medical Association of Thailand = Chotmaihet thangphaet [J Med Assoc Thai] 2014 Oct; Vol. 97 Suppl 10, pp. S105-9.
Abstrakt:	Background: Understanding the genetic etiologies of cleft lip and palate (CLP) is important for improved prevention, treatment, and prognosis for patients affected by CLP. Objective: To report the prevalence and the type of associated syndromes in Northeastern Thai patients with CLP. Material and Method: A retrospective study of123 cleft lip/palate children aged 4-5 years was carried out at the Tawanchai Cleft Centel; Khon Kaen University during the period from October to December 2011. Data were collected by reviewing the patient 's medical records. Results: Seventeen (14%) of the 123 children had multiple malformations and five (4%) of these children had associated syndromes. Syndromes were identified in 5 (29%) of the 17 children who had associated malformations. The syndromes were Apert, Cleft lip/palate-ectodermal dysplasia, Kabuki, Oculo-Auriculo-Vertebral Spectrum, and Velocardiofacial syndrome. Conclusion: Recognition of the associated syndrome in a patient with CLP is essential to assess the problem of the patient, provide necessaty treatment and the appropriate methodology of prevention.
Databáze:	MEDLINE
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