| Autor: |
Yim D; Department of Chemical Engineering, Hanyang University, Ansan 426-791, Republic of Korea. kjh75@hanyang.ac.kr., Kang H, Jeon SJ, Kim HI, Yang JK, Kang TW, Lee S, Choo J, Lee YS, Kim JW, Kim JH |
| Jazyk: |
angličtina |
| Zdroj: |
The Analyst [Analyst] 2015 May 21; Vol. 140 (10), pp. 3362-7. Date of Electronic Publication: 2015 Mar 26. |
| DOI: |
10.1039/c4an02382j |
| Abstrakt: |
Developing ultrasensitive Raman nanoprobes is one of the emerging interests in the field of biosensing and bioimaging. Herein, we constructed a new type of surface-enhanced resonance Raman scattering nanoprobe composed of an Ag nanoshell as a surface-enhanced Raman scattering-active nanostructure, which was encapsulated with 4,7,10-trioxa-1,13-tridecanediamine-functionalized graphene oxide as an ultrasensitive Raman reporter exhibiting strong resonance Raman scattering including distinct D and G modes. The designed nanoprobe was able to produce much more intense and simpler Raman signals even at a single particle level than the Ag nanoshell bearing a well-known Raman reporter, which is beneficial for the sensitive detection of a target in a complex biological system. Finally, this ultrasensitive nanoprobe successfully demonstrated its potential for bioimaging of cancer cells using Raman spectroscopy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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