Autor: |
Zubareva OE; Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia, zubarevaoe@mail.ru., Schwartz AP, Khnychenko LK, Ishchenko AM, Simbirtsev AS, Klimenko VM |
Jazyk: |
angličtina |
Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2015 Mar; Vol. 158 (5), pp. 607-10. Date of Electronic Publication: 2015 Mar 17. |
DOI: |
10.1007/s10517-015-2817-9 |
Abstrakt: |
Behavioral, hormonal, and neurotransmitter reactions to foot shock were studied in adult rats treated with IL-1β during week 3 of life. After stress, these animals differed from controls treated with saline by high levels of dopamine, serotonin, and 5-hydroxy-indolacetic acid in the hypothalamus. In contrast to controls, they developed a significant stress-induced increase of blood corticosterone level and exhibited lesser motor and exploratory activities in the open field test. |
Databáze: |
MEDLINE |
Externí odkaz: |
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