Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day.

Autor: Gardiner C; Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Level 3 Women's Centre, John Radcliffe Hospital, Oxford, UK; chris.gardiner@obs-gyn.ox.ac.uk., Harrison P; School of Immunity and Infection, University of Birmingham Medical School, Birmingham, UK., Belting M; Department of Oncology and Pathology, Clinical Sciences, Skåne University Hospital, Lund, Sweden., Böing A; Department of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands., Campello E; Department of Cardiologic, Thoracic and Vascular Sciences, University of Padua Medical School, Padua, Italy., Carter BS; Division of Neurosurgery, University of California San Diego, La Jolla, CA, USA., Collier ME; Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Wing, Glenfield General Hospital, Leicester, UK., Coumans F; Department of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands.; Department of Biomedical Engineering and Physics, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands., Ettelaie C; School of Biological, Biomedical and Environmental Sciences, The University of Hull, Hull, UK., van Es N; Department of Vascular Medicine, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands., Hochberg FH; Division of Neurosurgery, University of California San Diego, La Jolla, CA, USA.; Department of Neurology and Program in Neuroscience, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Mackman N; Thrombosis and Hemostasis Program, Department of Medicine, UNC McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Rennert RC; Division of Neurosurgery, University of California San Diego, La Jolla, CA, USA., Thaler J; Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Rak J; Department of Pediatrics, McGill University, Montreal Children's Hospital Research Institute MUHC, Montreal, QC, Canada., Nieuwland R; Department of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands.
Jazyk: angličtina
Zdroj: Journal of extracellular vesicles [J Extracell Vesicles] 2015 Mar 13; Vol. 4, pp. 26901. Date of Electronic Publication: 2015 Mar 13 (Print Publication: 2015).
DOI: 10.3402/jev.v4.26901
Abstrakt: Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor-bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. The International Society for Extracellular Vesicles (ISEV) and International Society on Thrombosis and Haemostasis (ISTH) held a joint Educational Day in April 2014 to discuss the latest developments in this field. This review discusses the themes of that event and the ISEV 2014 meeting that followed.
Databáze: MEDLINE