Portable gamma camera guidance in sentinel lymph node biopsy: prospective observational study of consecutive cases.

Autor: Peral Rubio F; Unidad de Gestión Clínica de Dermatología, Hospital Universitario Virgen Macarena, Sevilla, España. Electronic address: fperal@aedv.es., de La Riva P; Servicio de Medicina Nuclear, Hospital Universitario Virgen Macarena, Sevilla, España., Moreno-Ramírez D; Unidad de Gestión Clínica de Dermatología, Hospital Universitario Virgen Macarena, Sevilla, España., Ferrándiz-Pulido L; Unidad de Gestión Clínica de Dermatología, Hospital Universitario Virgen Macarena, Sevilla, España.
Jazyk: English; Spanish; Castilian
Zdroj: Actas dermo-sifiliograficas [Actas Dermosifiliogr] 2015 Jun; Vol. 106 (5), pp. 408-14. Date of Electronic Publication: 2015 Mar 09.
DOI: 10.1016/j.ad.2014.11.013
Abstrakt: Introduction: Sentinel lymph node biopsy is the most important tool available for node staging in patients with melanoma.
Objectives: To analyze sentinel lymph node detection and dissection with radio guidance from a portable gamma camera. To assess the number of complications attributable to this biopsy technique.
Methods: Prospective observational study of a consecutive series of patients undergoing radioguided sentinel lymph node biopsy. We analyzed agreement between nodes detected by presurgical lymphography, those detected by the gamma camera, and those finally dissected.
Results: A total of 29 patients (17 women [62.5%] and 12 men [37.5%]) were enrolled. The mean age was 52.6 years (range, 26-82 years). The sentinel node was dissected from all patients; secondary nodes were dissected from some. In 16 cases (55.2%), there was agreement between the number of nodes detected by lymphography, those detected by the gamma camera, and those finally dissected. The only complications observed were seromas (3.64%). No cases of wound dehiscence, infection, hematoma, or hemorrhage were observed.
Conclusions: Portable gamma-camera radio guidance may be of use in improving the detection and dissection of sentinel lymph nodes and may also reduce complications. These goals are essential in a procedure whose purpose is melanoma staging.
(Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved.)
Databáze: MEDLINE