Changing epidemiology of hepatitis C virus genotypes in the central region of Argentina.

Autor: Di Lello FA; Cátedra de Virología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina., Farias AA, Culasso AC, Pérez PS, Pisano MB, Contigiani MS, Campos RH, Ré VE
Jazyk: angličtina
Zdroj: Archives of virology [Arch Virol] 2015 Apr; Vol. 160 (4), pp. 909-15. Date of Electronic Publication: 2015 Mar 13.
DOI: 10.1007/s00705-015-2390-6
Abstrakt: The aim of this study was to analyze the prevalence of hepatitis C virus (HCV) genotypes in Córdoba province, Argentina, over a 12-year period and to study the changes at the molecular level. The HCV genotype was determined in 357 HCV-infected patients, and the phylogeny and demographic reconstruction for HCV-1 was assessed. A significant reduction in HCV-2 prevalence with respect to HCV-1 in Córdoba after 2003 was observed. These findings are consistent with the epidemiological changes observed in South America. Nevertheless, the consequences of these changes remain to be elucidated.
Databáze: MEDLINE