| Autor: |
Ivanov AN, Norkin IA, Puchin'ian DM, Shirokov VIu, Zhdanova OIu |
| Jazyk: |
ruština |
| Zdroj: |
Uspekhi fiziologicheskikh nauk [Usp Fiziol Nauk] 2014 Oct-Dec; Vol. 45 (4), pp. 34-49. |
| Abstrakt: |
The review presents current data concerning the functional role of endothelial cell adhesion molecules belonging to different structural families: integrins, selectins, cadherins, and the immunoglobulin super-family. In this manuscript the regulatory mechanisms and factors of adhesion molecules expression and distribution on the surface of endothelial cells are discussed. The data presented reveal the importance of adhesion molecules in the regulation of structural and functional state of endothelial cells in normal conditions and in pathology. Particular attention is paid to the importance of these molecules in the processes of physiological and pathological angiogenesis, regulation of permeability of the endothelial barrier and cell transmigration. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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