Levels of eicosapentaenoic acid in obese schoolchildren with and without insulin resistance.
| Autor: | Sánchez Meza K; Universidad de Colima, Facultad de Medicina. Av. Universidad 333, Colonia Las Víboras, Colima, Col., México. CP 28010.. carlostene1@hotmail.com., Tene Pérez CE; Universidad de Colima, Facultad de Medicina. Av. Universidad 333, Colonia Las Víboras, Colima, Col., México. CP 28010.. carlostene1@hotmail.com., Sánchez Ramírez CA; Universidad de Colima, Facultad de Medicina. Av. Universidad 333, Colonia Las Víboras, Colima, Col., México. CP 28010.. carlostene1@hotmail.com., Muñiz Valencia R; Universidad de Colima, Facultad de Ciencias Químicas. Kilómetro 9 carretera Colima-Coquimatlán, Col. México. CP 28400. México.. carlostene1@hotmail.com., Del Toro Equihua M; Universidad de Colima, Facultad de Medicina. Av. Universidad 333, Colonia Las Víboras, Colima, Col., México. CP 28010.. carlostene1@hotmail.com. |
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| Jazyk: | angličtina |
| Zdroj: | Nutricion hospitalaria [Nutr Hosp] 2014 Sep 12; Vol. 31 (3), pp. 1102-8. Date of Electronic Publication: 2014 Sep 12. |
| DOI: | 10.3305/nh.2015.31.3.8047 |
| Abstrakt: | Background: Obesity in children is now an increasing health risk worldwide in which the insulin-resistance can be present. Studies have linked a diet rich in n-3 fatty acids with a lower prevalence of insulin-resistance. Objective: To compare the levels of eicosapentaenoic acid among obese children with and without insulin-resistance. Materials and Methods: In 56 randomly school-age children with obesity, insulin-resistance was determined by the homeostasis model assessment for insulin-resistance index and the serum levels of eicosapentaenoic acid were determined by gas chromatography. Insulin-resistance was established when the index was >6.0, non- insulin- resistance when that index was within the range of 1.4-5.9. The serum levels of eicosapentaenoic acid were compared with the Kruskal-Wallis and Mann-Whitney U tests, as needed. Results: No differences in age or sex were identified among the groups studied. The anthropometric parameters were significantly higher in the group of children with insulin-resistance than in the other two groups. The children with insulin- resistance had significantly lower levels of eicosapentaenoic acid than the non- insulin-resistance group [12.4% area under the curve vs. 37.4%, p = 0.031], respectively. Conclusion: Obese primary school-aged children with insulin-resistance had lower plasma levels of eicosapentaenoic acid. (Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.) |
| Databáze: | MEDLINE |
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