[Pertussis vaccine. Reemergence of the disease and new vaccination strategies].

Autor:	Moraga-Llop FA; Societat Catalana de Pediatria, Asociación Española de Vacunología, Barcelona, España. Electronic address: fmoraga@acmcb.es., Campins-Martí M; Servicio de Medicina Preventiva y Epidemiología, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, España.
Jazyk:	Spanish; Castilian
Zdroj:	Enfermedades infecciosas y microbiologia clinica [Enferm Infecc Microbiol Clin] 2015 Mar; Vol. 33 (3), pp. 190-6. Date of Electronic Publication: 2015 Feb 20.
DOI:	10.1016/j.eimc.2015.02.001
Abstrakt:	Pertussis continues to be a public health problem despite the significant decrease in its incidence due to routine vaccination. Resurgence of the disease in countries that have maintained high vaccination coverage has been observed in recent years. Although vaccination is the most effective preventive control measure, both natural and artificial immunity wane over time, and thus the protection offered by current vaccines is not long-lasting. Furthermore, acellular vaccines are less effective. The implementation of new vaccine strategies is required. Vaccination of pregnant women is the most effective strategy for preventing pertussis in young infants, who are the most vulnerable, and should be recommended together with cocooning, ie vaccination of future household and extra-domiciliary contacts who are the main transmitters of the disease. (Copyright © 2015 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.)
Databáze:	MEDLINE
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