| Autor: |
Frolova NIu, Printsev MD, Tret'iakov AV, Kozhetiakin LA, Korovkin BF |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy meditsinskoi khimii [Vopr Med Khim] 1989 Jan-Feb; Vol. 35 (1), pp. 64-8. |
| Abstrakt: |
Distinct increase and then decrease in content of cyclic nucleotides was observed in dog myocardium ventricles and auricles within early periods of heart infarction (10 min-4 hrs). Within a day after ligation of artery the ratio cAMP/cGMP was considerably decreased as a result of activation of guanylate cyclase and cAMP-phosphodiesterase as well as due to a decrease in activity of adenylate cyclase. Acute ischemia of small area of the heart left ventricle caused impairment of cyclic nucleotide metabolism in all the heart muscle. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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