Prevalence of hyposalivation in patients with systemic lupus erythematosus in a brazilian subpopulation.

Autor: Leite CA; Department of Oral Pathology, University of Cuiabá, Avenida Manoel José de Arruda 3.100 Jardim Europa, 78065-900 Cuiabá, MT, Brazil ; Department of Pathology, Federal Fluminense University, Rua Marquês do Paraná 303, No. 4 Andar do Prédio Principal, Sala 1, 24.033-900 Niterói, RJ, Brazil., Galera MF; Department of Pediatrics, School of Medicine, Federal University of Mato Grosso, Avenida Fernando Corrêa da Costa 2367, Boa Esperança, 78060-900 Cuiabá, MT, Brazil., Espinosa MM; Department of Statistics, Institute of Exact Sciences, Federal University of Mato Grosso, Avenida Fernando Corrêa da Costa 2367, Boa Esperança, 78060-900 Cuiabá, MT, Brazil., de Lima PR; School of Dentistry, University of Cuiabá, Brazil Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil., Fernandes V; Department of Rheumatology, University of Cuiabá, Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil., Borges ÁH; Faculty of Dentistry, University of Cuiabá, Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil., Dias EP; Department of Pathology, Federal Fluminense University, Rua Marquês do Paraná 303, No. 4 Andar do Prédio Principal, Sala 1, 24.033-900 Niterói, RJ, Brazil.
Jazyk: angličtina
Zdroj: International journal of rheumatology [Int J Rheumatol] 2015; Vol. 2015, pp. 730285. Date of Electronic Publication: 2015 Jan 11.
DOI: 10.1155/2015/730285
Abstrakt: Background. Systemic lupus erythematosus (SLE) is a chronic inflammatory, multisystem, and autoimmune disease. Objective. The aim of this study was to describe the prevalence of hyposalivation in SLE patients and evaluate factors associated. Methods. This is a cross-sectional study developed at the Cuiaba University General Hospital (UNIC-HGU), Mato Grosso, Brazil. The study population consisted of female SLE patients treated at this hospital from 06/2010 to 12/2012. Unstimulated salivary flow rates (SFRs) were measured. Descriptive and inferential analyses were performed in all cases using a significance level P < 0.05. Results. The results showed that 79% of patients with systemic lupus erythematosus suffered from hyposalivation and that the disease activity and age in years were the factors that resulted in statistically significant differences. Conclusion. The activity of the disease, age >27 years, and the drugs used were factors associated with hyposalivation, resulting in a statistically significant decrease in saliva production.
Databáze: MEDLINE