A nuclear singlet lifetime of more than one hour in room-temperature solution.

Autor: Stevanato G; School of Chemistry, University of Southampton, University Road, Southampton, SO17 1BJ (UK)., Hill-Cousins JT, Håkansson P, Roy SS, Brown LJ, Brown RC, Pileio G, Levitt MH
Jazyk: angličtina
Zdroj: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2015 Mar 16; Vol. 54 (12), pp. 3740-3. Date of Electronic Publication: 2015 Jan 28.
DOI: 10.1002/anie.201411978
Abstrakt: Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are supremely important techniques with numerous applications in almost all branches of science. However, until recently, NMR methodology was limited by the time constant T1 for the decay of nuclear spin magnetization through contact with the thermal molecular environment. Long-lived states, which are correlated quantum states of multiple nuclei, have decay time constants that may exceed T1 by large factors. Here we demonstrate a nuclear long-lived state comprising two (13)C nuclei with a lifetime exceeding one hour in room-temperature solution, which is around 50 times longer than T1. This behavior is well-predicted by a combination of quantum theory, molecular dynamics, and quantum chemistry. Such ultra-long-lived states are expected to be useful for the transport and application of nuclear hyperpolarization, which leads to NMR and MRI signals enhanced by up to five orders of magnitude.
(© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Databáze: MEDLINE
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