Autor: |
Gungor B; Department of Biological Sciences; Middle East Technical University ; Ankara, Turkey., Yagci FC; Department of Molecular Biology and Genetics Bilkent University ; Ankara, Turkey., Gursel I; Department of Molecular Biology and Genetics Bilkent University ; Ankara, Turkey., Gursel M; Department of Biological Sciences; Middle East Technical University ; Ankara, Turkey. |
Jazyk: |
angličtina |
Zdroj: |
Oncoimmunology [Oncoimmunology] 2014 Jul 03; Vol. 3 (7), pp. e950166. Date of Electronic Publication: 2014 Jul 03 (Print Publication: 2014). |
DOI: |
10.4161/21624011.2014.950166 |
Abstrakt: |
Type I interferon inducers may potentially be engineered to function as antiviral and anticancer agents, or alternatively, vaccine adjuvants, all of which may have clinical applications. We recently described a simple strategy to convert a Toll-like receptor 9 (TLR9) agonist devoid of interferon α (IFNα) stimulating activity into a robust Type I interferon inducer with potent vaccine adjuvant activity. |
Databáze: |
MEDLINE |
Externí odkaz: |
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