| Autor: |
Telina EN, Kirshin SV, Nizamov RS, Akhmedzianov RKh, Khamitov KhS |
| Jazyk: |
ruština |
| Zdroj: |
Neirofiziologiia = Neurophysiology [Neirofiziologiia] 1989; Vol. 21 (6), pp. 735-41. |
| Abstrakt: |
Radioassay binding of the smooth muscle of the nictitating membrane of cat has revealed the specific binding sites of [3H]prazosin corresponding to alpha-1 adrenoceptors. There was a significant increase in the number of alpha-1 adrenoceptors without any changes in their affinity. Incubation of the culture of the preliminary sympathectomized smooth muscle with noradrenaline decreased the number of alpha-1 adrenoceptors also without altering the affinity of binding. So, it is concluded that sympathetic nervous system regulated the number of postsynaptic alpha-1 adrenoceptors by means of neurotransmitter (noradrenaline). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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