Vitamin A-fortified cooking oil reduces vitamin A deficiency in infants, young children and women: results from a programme evaluation in Indonesia.

Autor:	Sandjaja; 1National Institute for Health Research and Development (NIHRD),Ministry of Health,Republic of Indonesia,Jakarta,Indonesia., Jus'at I; 2Indonesian Nutrition Foundation for Food Fortification (formerly Koalisi Fortifikasi Indonesia),Jakarta,Indonesia., Jahari AB; 1National Institute for Health Research and Development (NIHRD),Ministry of Health,Republic of Indonesia,Jakarta,Indonesia., Ifrad; 2Indonesian Nutrition Foundation for Food Fortification (formerly Koalisi Fortifikasi Indonesia),Jakarta,Indonesia., Htet MK; 5Center of Community Health and Population Studies,The Research Institute,Trisakti University,Jakarta,Indonesia., Tilden RL; 2Indonesian Nutrition Foundation for Food Fortification (formerly Koalisi Fortifikasi Indonesia),Jakarta,Indonesia., Soekarjo D; 6Savica Public Health Nutrition & Communication Consultancy,Surabaya,Indonesia., Utomo B; 7University of Indonesia School of Public Health,Jakarta,Indonesia., Moench-Pfanner R; 8Global Alliance for Improved Nutrition,Singapore., Soekirman; 2Indonesian Nutrition Foundation for Food Fortification (formerly Koalisi Fortifikasi Indonesia),Jakarta,Indonesia., Korenromp EL; 9Global Alliance for Improved Nutrition,PO Box 55,1211 Geneva 20,Switzerland.
Jazyk:	angličtina
Zdroj:	Public health nutrition [Public Health Nutr] 2015 Oct; Vol. 18 (14), pp. 2511-22. Date of Electronic Publication: 2015 Jan 16.
DOI:	10.1017/S136898001400322X
Abstrakt:	Objective: To assess oil consumption, vitamin A intake and retinol status before and a year after the fortification of unbranded palm oil with retinyl palmitate. Design: Pre-post evaluation between two surveys. Setting: Twenty-four villages in West Java. Subjects: Poor households were randomly sampled. Serum retinol (adjusted for subclinical infection) was analysed in cross-sectional samples of lactating mothers (baseline n 324/endline n 349), their infants aged 6-11 months (n 318/n 335) and children aged 12-59 months (n 469/477), and cohorts of children aged 5-9 years (n 186) and women aged 15-29 years (n 171), alongside food and oil consumption from dietary recall. Results: Fortified oil improved vitamin A intakes, contributing on average 26 %, 40 %, 38 %, 29 % and 35 % of the daily Recommended Nutrient Intake for children aged 12-23 months, 24-59 months, 5-9 years, lactating and non-lactating women, respectively. Serum retinol was 2-19 % higher at endline than baseline (P<0·001 in infants aged 6-11 months, children aged 5-9 years, lactating and non-lactating women; non-significant in children aged 12-23 months; P=0·057 in children aged 24-59 months). Retinol in breast milk averaged 20·5 μg/dl at baseline and 32·5 μg/dl at endline (P<0·01). Deficiency prevalence (serum retinol <20 μg/dl) was 6·5-18 % across groups at baseline, and 0·6-6 % at endline (P≤0·011). In multivariate regressions adjusting for socio-economic differences, vitamin A intake from fortified oil predicted improved retinol status for children aged 6-59 months (P=0·003) and 5-9 years (P=0·03). Conclusions: Although this evaluation without a comparison group cannot prove causality, retinyl contents in oil, Recommended Nutrient Intake contributions and relationships between vitamin intake and serum retinol provide strong plausibility of oil fortification impacting vitamin A status in Indonesian women and children.
Databáze:	MEDLINE
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