Sarcoidosis, a report from Guilan (an Iranian northen province) (2001-09).

Autor: Foumani AA; Guilan university of medical sciences. aalavi_foumani@yahoo.com., Akhoundzadeh N, Karkan MF
Jazyk: angličtina
Zdroj: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG [Sarcoidosis Vasc Diffuse Lung Dis] 2015 Jan 05; Vol. 31 (4), pp. 282-8. Date of Electronic Publication: 2015 Jan 05.
Abstrakt: Background: Sarcoidosis is a chronic multiorgan autoimmune disorder that affects all racial and ethnic groups and occurs at all ages.
Objective: The aim of this study was to assess the clinical and epidemiological features of sarcoidosis patients in a referral clinic of pulmonary disease in city of Rasht (Guilan-Iran).
Method: This retrospective study was done by reviewing sarcoidosis patient's records containing demographic, sign and symptom and clinical data in a pulmonary clinic in Rasht from 2001-09. All statistical analyses were achieved using SPSS.
Results: most common signs and symptoms were respiratory, systemic and musculoskeletal complaints. According to Chest X-Ray, 61.3% had bilateral hilar lymphadenopathy (BHL) alone (stage 1), and 24.2% had BHL plus parenchymal involvment (stage 2). The most common abnormal finding in spirometry was small airway disease (20.3%).The follow-up data showed that 178 patients (45.2%) had significant improvement clinically, radiologically or both.
Conclusion: It seems many clinical and radiological aspects of sarcoidosis in our patients are similar to other series. However, presentation with Lofgren's syndrome is a common feature and skin (n=48, 12.3%) and eye (n=19, 4.8%) involvement are less frequent. There is significant difference between west and east of Guilan in relation to referred patients (12.9 % vs 78.5% respectively).Of course this may be due to referral issues of patients and medical teamwork connections
Databáze: MEDLINE