Clinicopathologic evaluation of lesions associated with tobacco usage.

Autor:	Samatha Y; Associate Professor, Department of Oral Medicine and Radiology, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India, e-mail: saisamata@gmail.com., Sankar AJ; Professor and Head, Department of Pedodontics and Preventive Dentistry, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India., Ganapathy KS; Former Principal and Head, Department of Oral Medicine and Radiology, The Oxford Dental College and Research Centre, Bengaluru, Karnataka India., Srinivas K; Professor, Department of Oral Medicine and Radiology, ACES Maruthi Dental College, Bengaluru, Karnataka, India., Ankineedu D; Resident, Department of Oral Medicine, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India., Choudary AL; Private Practitioner, Guntur, Andhra Pradesh, India.
Jazyk:	angličtina
Zdroj:	The journal of contemporary dental practice [J Contemp Dent Pract] 2014 Jul 01; Vol. 15 (4), pp. 466-72. Date of Electronic Publication: 2014 Jul 01.
DOI:	10.5005/jp-journals-10024-1564
Abstrakt:	Introduction: Tobacco usage in different forms is the single most common etiological factor responsible for oral cancers. The aim of the present study was to record various mucosal lesions associated with tobacco usage and to ascertain the prevalence of dysplasia in them by histopathological evaluation and to compare the extent of dysplastic features seen among patients associated with a habit of smoked and smokeless form of tobacco. Materials and Methods: Seventy-six patients with the clinical diagnosis of tobacco related lesions (Leukoplakia, Erythroplakia, Nicotina stomatitis, Tobacco pouch keratosis) were selected. A detailed description of the clinical presentation of the lesion was noted and the patients were subjected to incisional biopsy followed by a histopathological evaluation. Results: Showed dysplastic changes in 50 cases (65.8%) ranging from mild dysplasia in 27 cases (35.5%), moderate dysplasia in 17 cases (22.4%) and 6 cases (7.9%) showed severe dysplasia. Moderate to severe dysplasia was 1.83 times more likely to occur with smokeless tobacco usage when compared to smoked form. Data obtained from this study reveals that patients with a duration of tobacco usage more than 10 years were 2.17 times more likely to have moderate to severe dysplasia (p = 0.154). Conclusion: Thus, the study highlights the role of oral physicians in detecting oral mucosal lesions and screening high-risk patients on a regular basis and also reaffrms the importance of public education, stressing the risk factors for oral cancers.
Databáze:	MEDLINE
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