Bilateral lid/brow elevation procedure for severe ptosis in Kearns-Sayre syndrome, a mitochondrial cytopathy.

Autor: Sebastiá R; Department of Ophthalmology, Fluminense Federal University, Niterói, Brazil ; Oculoplastic Surgery Department, 38th Infirmary of the Santa Casa de Misericordia do Rio de Janeiro, Instituto Ivo Pitanguy, Pontifícia Universidade Catolica do Rio de Janeiro, Rio de Janeiro, Brazil., Fallico E; Clinica Gretter, Università degli Studi di Catania, Catania, Italy., Fallico M; Facoltà di Medicina e Chirurgia, Università degli Studi di Catania, Catania, Italy., Fortuna E; Hospital da Plástica, State University of Rio de Janeiro, Rio de Janeiro, Brazil., Lessa S; Oculoplastic Surgery Department, 38th Infirmary of the Santa Casa de Misericordia do Rio de Janeiro, Instituto Ivo Pitanguy, Pontifícia Universidade Catolica do Rio de Janeiro, Rio de Janeiro, Brazil ; Post-Graduate Program in Physiopathology in Surgical Science, State University of Rio de Janeiro, Rio de Janeiro, Brazil., Neto GH; Department of Ophthalmology, Fluminense Federal University, Niterói, Brazil.
Jazyk: angličtina
Zdroj: Clinical ophthalmology (Auckland, N.Z.) [Clin Ophthalmol] 2014 Dec 22; Vol. 9, pp. 25-31. Date of Electronic Publication: 2014 Dec 22 (Print Publication: 2015).
DOI: 10.2147/OPTH.S74179
Abstrakt: Background: The purpose of this work was to determine the effectiveness and possible complications encountered with bilateral fascia lata lid suspension used to correct blepharoptosis in patients with Kearns-Sayre syndrome.
Methods: This was a retrospective study of seven patients with Kearns-Sayre syndrome who had a minimum of 1 year of follow-up. A bilateral fascia lata sling was used to correct the ptosis. Preoperative and postoperative measurements of the vertical lid fissure width (VFW) and marginal reflex distance (MRD) were performed. The Student's t-test was used to analyze the results.
Results: The mean preoperative VFW and MRD measurements were 4±2.45 mm and 0.14±0.92 mm, respectively. The mean postoperative VFW and MRD measurements were 7.71±1.85 mm, and 2.86±1.69 mm, respectively. All preoperative and postoperative values were considered to be statistically significant (P<0.01). Adequate elevation of the lids was obtained in all patients, both functionally and aesthetically. All of the patients showed a mild symmetric postoperative inferior version lagophthalmos, and one patient developed corneal ulceration and scarring due to corneal exposure and a weak Bell's phenomenon.
Conclusion: The surgical technique described to correct the blepharoptosis found in patients with Kearns-Sayre syndrome was found to be efficient and relatively safe. The correction should be conservative to decrease the risk of postoperative corneal damage that occurred in one patient.
Databáze: MEDLINE