Life-threatening hemorrhaging in neonatal ulcerated congenital hemangioma: two case reports.

Autor:	Vildy S; Department of Dermatology, Nantes University Hospital, Nantes, France., Macher J; Department of Intensive Care of Neonatology, Nantes University Hospital, Nantes, France., Abasq-Thomas C; Department of Dermatology, Brest University Hospital, Brest, France., Le Rouzic-Dartoy C; Department of Infantile Surgery, Brest University Hospital, Brest, France., Brunelle F; Department of Interventional Radiology and Dermatology, Necker Enfants Malades University Hospital, Paris, France., Hamel-Teillac D; Department of Interventional Radiology and Dermatology, Necker Enfants Malades University Hospital, Paris, France., Duteille F; Department of Vascular and Plastic Surgery, Nantes University Hospital, Nantes, France., Perret C; Department of Vascular and Plastic Surgery, Nantes University Hospital, Nantes, France., Perrot P; Department of Vascular and Plastic Surgery, Nantes University Hospital, Nantes, France., Cassagnau E; Department of Histology, Nantes University Hospital, Nantes, France., Chauty-Frondas A; Department of Intensive Care of Neonatology, Nantes University Hospital, Nantes, France., Aubert H; Department of Dermatology, Nantes University Hospital, Nantes, France., Barbarot S; Department of Dermatology, Nantes University Hospital, Nantes, France.
Jazyk:	angličtina
Zdroj:	JAMA dermatology [JAMA Dermatol] 2015 Apr; Vol. 151 (4), pp. 422-5.
DOI:	10.1001/jamadermatol.2014.3666
Abstrakt:	Importance: Congenital hemangiomas (CHs) are rare benign vascular tumors that differ from common infantile hemangiomas in that they grow in utero and are fully developed at birth. While ulceration is a common, predominantly benign complication in infantile hemangioma, little is known about the prognosis of ulcerated CH. However, it has been observed that ulcerated CH may be complicated by life-threatening bleeding episodes. Observations: We report 2 cases of ulcerated rapidly involuting congenital hemangiomas (RICH) that were complicated by life-threatening bleeding episodes in the neonatal period. In both cases, the CHs were fed by high-flow vessels and the ensuing massive bleeding was due to superficial vessel wall erosion induced by the ulceration. Both patients were successfully treated with intravascular embolization; one patient underwent additional hemostatic surgery. Conclusions and Relevance: These 2 cases highlight the importance of closely monitoring children with ulcerated CH because of the risk of severe bleeding. Embolization is the treatment of choice in the case of severe bleeding, as the natural history of RICH is to spontaneously regress.
Databáze:	MEDLINE
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