Open access integrated therapeutic and diagnostic platforms for personalized cardiovascular medicine.

Autor: Gladding PA; Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. patrickg@theranosticslab.com., Cave A; Waitemata District Health Board, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. andrew.cave@waitematadhb.govt.nz., Zareian M; Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. andrew.cave@waitematadhb.govt.nz., Smith K; Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. andrew.cave@waitematadhb.govt.nz., Hussan J; Auckland Bioengineering Institute, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. r.jagir@auckland.ac.nz., Hunter P; Auckland Bioengineering Institute, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. p.hunter@auckland.ac.nz., Erogbogbo F; Institute for Lasers, Photonics and Biophotonics, 428 Natural Science Complex, University at Buffalo, NY 14260-3000, USA. erogbogbo@gmail.com., Aguilar Z; Ocean NanoTech, 2143 Worth Lane, Springdale, AR 72764, USA. zapaguilar@yahoo.com., Martin DS; Wyle Science, Technology and Engineering Group, 1200 Hercules, Houston, TX 77058, USA. david.s.martin@nasa.gov., Chan E; DNA Medicine Institute, 727 Massachusetts Avenue, Cambridge, MA 02139, USA. echan@dnamedinstitute.com., Homer ML; Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, USA. margie.l.homer@jpl.nasa.gov., Shevade AV; Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, USA. abhijit.v.shevade@jpl.nasa.gov., Kassemi M; NASA Glenn Research Center, 21000 Brookpark Rd, Cleveland, OH 44135, USA. mohammad.kassemi@nasa.gov., Thomas JD; Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. thomasj@ccf.org., Schlegel TT; Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. ttschlegel@gmail.com.
Jazyk: angličtina
Zdroj: Journal of personalized medicine [J Pers Med] 2013 Aug 21; Vol. 3 (3), pp. 203-37. Date of Electronic Publication: 2013 Aug 21.
DOI: 10.3390/jpm3030203
Abstrakt: It is undeniable that the increasing costs in healthcare are a concern. Although technological advancements have been made in healthcare systems, the return on investment made by governments and payers has been poor. The current model of care is unsustainable and is due for an upgrade. In developed nations, a law of diminishing returns has been noted in population health standards, whilst in the developing world, westernized chronic illnesses, such as diabetes and cardiovascular disease have become emerging problems. The reasons for these trends are complex, multifactorial and not easily reversed. Personalized medicine has the potential to have a significant impact on these issues, but for it to be truly successful, interdisciplinary mass collaboration is required. We propose here a vision for open-access advanced analytics for personalized cardiac diagnostics using imaging, electrocardiography and genomics.
Databáze: MEDLINE
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