Autor: |
Wang X, Ahmed NB, Alvarez GS, Tuttolomondo MV, Hélary C, Desimone MF, Coradin T; Chimie de la Matiere Condensee, College de France, 11 place Marcelin Berthelot, 75005 Paris, France. thibaud.coradin@upmc.fr. |
Jazyk: |
angličtina |
Zdroj: |
Current topics in medicinal chemistry [Curr Top Med Chem] 2015; Vol. 15 (3), pp. 223-44. |
DOI: |
10.2174/1568026614666141229112734 |
Abstrakt: |
The sol-gel process provides a robust and versatile technology for the immobilization of biologicals. A wide range of inorganic, composites and hybrid materials can be prepared to encapsulate molecular drugs, proteins, antibodies/antigens, enzymes, nucleic acids, prokaryotic and eukaryotic cells into bulk gels, particles and films. This review describes the applications of sol-gel encapsulation relevant to medicinal chemistry focusing on the recent development of biosensors as well as systems for production, screening and delivery of bioactive compounds and biomaterials. |
Databáze: |
MEDLINE |
Externí odkaz: |
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