An update on 2,5-diketopiperazines from marine organisms.

Autor: Huang RM; Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. prsxs@bath.ac.uk., Yi XX; School of Pharmaceutical Sciences, Guangxi University of Chinese Medicine, Nanning 530001, China. xiangxiyi81@aliyun.com., Zhou Y; Department of Cell Biology, Jinan University, Guangzhou 510632, China. chenlu0268@163.com., Su X; Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK. prsxs@bath.ac.uk., Peng Y; Life Science & Technology School, Lingnan Normal University, Zhanjiang 52048, China. py00_2006@126.com., Gao CH; Key Laboratory of Marine Environmental Science, Guangxi Academy of Sciences, Nanning 530007, China. gaochenghai@gxas.cn.
Jazyk: angličtina
Zdroj: Marine drugs [Mar Drugs] 2014 Dec 19; Vol. 12 (12), pp. 6213-35. Date of Electronic Publication: 2014 Dec 19.
DOI: 10.3390/md12126213
Abstrakt: 2,5-Diketopiperazines (2,5-DKPs) are an important category of structurally diverse cyclic dipeptides with prominent biological properties. These 2,5-DKPs have been obtained from a variety of natural resources, including marine organisms. Because of the increasing numbers and biological importance of these compounds, this review covers 90 marine originated 2,5-DKPs that were reported from 2009 to the first half-year of 2014. The review will focus on the structure characterizations, biological properties and proposed biosynthetic processes of these compounds.
Databáze: MEDLINE