| Autor: |
Yau GSK; From the Department of Ophthalmology, Caritas Medical Centre (GSKY, JWYL, VTYT); Department of Ophthalmology, The University of Hong Kong (JWYL, IYHW); Department of Applied Mathematics, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China (CCLL)., Lee JWY, Tam VTY, Liu CCL, Wong IYH |
| Jazyk: |
angličtina |
| Zdroj: |
Medicine [Medicine (Baltimore)] 2014 Dec; Vol. 93 (28), pp. e314. |
| DOI: |
10.1097/MD.0000000000000314 |
| Abstrakt: |
To investigate the incidence and risk factors of retinopathy of prematurity (ROP) and Type 1 ROP in extremely preterm Chinese infants. A retrospective review of medical records was performed of all extremely preterm neonates (gestational age, GA≤28 weeks) screened for ROP from 2007 to 2012 at an ophthalmology centre in Hong Kong. Thirty-three maternal and neonatal covariates were analyzed using univariate and multivariate regression analyses for both ROP and Type 1 ROP. The mean gestational age (GA) was 26.4±1.3 weeks and the birth weight (BW) was 855.0±199.0 g. The incidence of ROP development was 60.7% and 16.2% for Type 1 ROP. On univariate analysis, 6 risk factors were identified for ROP development including: lighter BW; lower GA; postnatal hypotension; inotrope use; surfactant use; and invasive mechanical ventilation (all P≤0.01). On multivariate analysis, neonatal congenital heart disease and greater GA were protective factors for ROP development (P≤0.04). On the other hand, 4 risk factors were associated with Type 1 ROP development in univariate analysis, including: lower GA, lighter BW, multiple pregnancies, and invasive mechanical ventilation (all P≤0.02); while there was no significant risk factors on multivariate analysis. A lighter BW and lower GA were the only common independent risk factors for both ROP and Type 1 ROP while neonatal congenital heart disease and greater GA were the protective factors against ROP. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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