Genetic counselors' (GC) knowledge, awareness, understanding of clinical next-generation sequencing (NGS) genomic testing.

Autor: Boland PM; Roswell Park Cancer Institute, Department of Medicine, Medical Oncology, Buffalo, NY, USA., Ruth K; Fox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA., Matro JM; Fox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA., Rainey KL; Fox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA., Fang CY; Fox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA., Wong YN; Fox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA., Daly MB; Fox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA., Hall MJ; Fox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA.
Jazyk: angličtina
Zdroj: Clinical genetics [Clin Genet] 2015 Dec; Vol. 88 (6), pp. 565-72. Date of Electronic Publication: 2015 Jan 22.
DOI: 10.1111/cge.12555
Abstrakt: Genomic tests are increasingly complex, less expensive, and more widely available with the advent of next-generation sequencing (NGS). We assessed knowledge and perceptions among genetic counselors pertaining to NGS genomic testing via an online survey. Associations between selected characteristics and perceptions were examined. Recent education on NGS testing was common, but practical experience limited. Perceived understanding of clinical NGS was modest, specifically concerning tumor testing. Greater perceived understanding of clinical NGS testing correlated with more time spent in cancer-related counseling, exposure to NGS testing, and NGS-focused education. Substantial disagreement about the role of counseling for tumor-based testing was seen. Finally, a majority of counselors agreed with the need for more education about clinical NGS testing, supporting this approach to optimizing implementation.
(© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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